The most bizarre mewgenic mutations

Mewgenics completely exploded into a villainous landscape, bringing with it plenty of blood, grime, and plenty of weirdness that has long been a hallmark Isaac developers. One of the game's central mechanics is breeding, which allows players to mix and match the stats and abilities of two cats in hopes of creating a stronger cat to take on your next run.

mewgenic tips and tricks

Mewgenic tips and tricks

Want to get the most out of your cats and every run in Mewgenics? Check out our tips and tricks to help you get through this creepy cat adventure.

However, just like in real life, the process of giving birth is not always a walk in the park, and in this case, many cats can end up with some special mutations that give them unique effects while changing their appearance in very drastic ways. Many of these changes come with a few basic stat changes, but some go even further and give players an incredibly unique party member that looks weird and has some extra surprises in store for them as well.

Long legs

Far above danger

Mewgenics Long legs

Details:

  • This unit is immune to any tile effects

Players who played even a little bit Binding of Isaac: Rebirth he will know all about Daddy Long Legs and the multitude of things related to his elongated limbs. Now inside Mewgenicsthe trend continues, with a big mutation that pulls the cat high above all dangers, at least those lying on the ground.

Not only does the little kitten look incredibly silly, especially on the battlefield, but it also serves a functional purpose that is incredibly powerful in certain stages like the Boneyard, with all that broken glass. The ability to dodge ground effects can reduce and even nullify many enemies, making it a powerful, if odd, mutation.

Cat limbs

Far more than nine lives

Mewgenics

Details:

  • Spawn Charmed Kitten familiar when you are shot down.

Lots of mutations in Mewgenics they're either visually or mechanically absurd, but this manages to tick both boxes at once. The effect can come from many different sources, such as the cat's legs or even its body, the latter of which makes them downright scary long before they enter combat.

mewgenic battle guide

Mewgenics Combat Guide

Mewgenics is heavily focused on combat, so knowing how to fight comes naturally, and this guide will help you do exactly that.

The actual perk is also just as unusual as it gives players an extra unit that can help them out in tricky situations where the cat goes down. Thematically, it's almost as if the mutation has jumped from a corpse into combat, an image that's somehow more peculiar than the effect itself.

Wings

Who said cats can't fly?

Mewgenics Wings

Details:

  • +2 speed

  • Fly away when hit.

As players progress through the run, they will encounter several passive birds that aimlessly run around and fly away from anything that swings at them. Once he's chasing them, the stat buff is pretty handy, making them a great focus point, although they can be a bit slippery to catch.

If players are lucky, they can actually get this effect for themselves by using a pair of wings to allow their unit to escape in the middle of combat without having to move. The extra speed is also useful as it allows them to later relocate wherever necessary, making it a decently powerful mutation for movement-loving cats.

Bone ears

Becoming one with the dead

Mewgenic bone ear

Details:

  • Whenever you defeat a unit, you have a 10% chance to revive that unit with 50% HP.

After clearing the Boneyard and fighting the devious Dybbuk, players are rewarded with the Necromancer Collar, which brings with it some interesting new effects such as reviving corpses. The ability to bring units back from the dead is incredibly powerful given how good summoners are in the game, and whenever players get the chance to do so, they should be more than happy to have a little zombie running around for them.

The bone mutation adds to this idea, giving players a passive effect that has a random chance to respawn units whenever they shoot down an enemy. While the summon is weaker than the actual enemy itself, any extra body is nice to have, and the fact that it comes from a mutation and not an active spell is why it's so powerful and more than enough reason to add the poor kitty to the party.

Place 9 games in the grid.

Place 9 games in the grid.

Lazy eye

It's not time to sleep

Mewgenics late turnaround

Details:

  • Use initiative -20

  • Take your turn later

Because Mewgenics is a turn-based game, many players from D&D the world will feel right at home with their knowledge of mechanics like initiative. The stats effectively dictate which unit attacks in which order, with a higher number meaning an earlier turn and vice versa, so it's important to understand from the start.

However, this mutation completely ignores the need to act and instead keeps the cat in a stationary position for much longer than it probably needs to. It's probably one of the worst mutations in the game, as the -20 debuff can mean a unit misses several rounds at once, which can be all it takes to turn an otherwise winnable fight into an instant loss.

Isaac Eye

Lots of Tears Left

Mewgenics Isaac

Details:

  • +1 Divine Shield

  • Your basic attack creates water tiles.

It may not be his game, but Isaac still is in some shape or form. This weeping mutation gives players a water effect to their basic attack, which fits nicely thematically and actually proves to be surprisingly effective given how useful movement slows are in the game.

mewgenics stats guide header

All Mewgenics Cat Stats (And What They Do)

As you venture further from home in Mewgenics, you'll face tougher enemies. This means you'll need cats with better stats.

The DivineShield it comes with is another great bonus, allowing the cat to block an entire attack at once, making the mutation stronger overall. From an easter egg point of view, this could be a callback to The Lost, a character in Isaac which begins its run with a similar shield item while also having signature crying attacks that have now been carried over into a completely different experience.

Stern head

Everything from back to front

Mewgenics murder

Details:

  • Attacks against your face count as backstabs.

Backstabs are a crucial mechanic in the game that can give players a huge advantage in virtually any fight. They work on both allies and enemies, and aside from the obvious Thief class advantages, this should be something players incorporate into their future runs if they want some extra free damage.

This mutation has friendly jabs in the back and makes them apply from the front as well, making the cat a prime target for heavy hits. Connotations aside, there is one synergy that can really benefit from this otherwise terrible disadvantage, and that is the Frying Pan item, which not only blocks all backstab damage, but also allows the player to counterattack, turning the mutation into a surprisingly powerful one in the right situation.

Gemini head

Two heads are better than one

Mewgenics twins

Details:

  • Turn extra at the start of battle.

Actions and moves are essential components of any successful run, as if players can't dish out enough damage quickly, they can soon be outmatched and outmatched by their enemies. However, with enough speed and a few recovery abilities, players can abuse move orders and traditional action sequences to squeeze in some extra abilities before enemies even react.

This mutation goes above and beyond, giving players an extra turn to use early on, which can easily be an insane bonus when used correctly. They could set up for a crazy early turn or save mana and cast a heavy spell earlier, so if they overlook the obvious warp, it could easily become the player's next favorite mutation.

Dead mouth

Greatest bodies ever

Mewgenics' corpse

Details: t

Corpse health is a very important part of combat Mewgenicsas it allows a downed ally to remain salvageable even if things go completely awry. As long as they don't get smacked around too much, they'll stand up after fighting the rest of the team, though they'll suffer stat loss as a penalty for being knocked out.

However, the base three health is still pretty low, so why not add another 100 to make sure the cat is okay? This little mutation can be the centerpiece of an entire build, as players can quite happily send in a sacrificial unit, knowing full well that there's no way enemies can deal even close to lethal damage before the entire fight is over.

A leg with a syringe

Say yes to drugs

Mewgenics syringe leg

Details:

  • Your basic attack will cause a random debuff

  • Apply +1 randomly from: Poison, Burn, Bleed, Blind, Weakness

Isaac players will know all about the various syringes in the game as they are all pretty useful items to grab, although some are slightly better in terms of effectiveness. In this case, the same power remains, because despite clearly destroying the cat's day, this mutation is actually insanely good against and against virtually every unit in the game.

Each attack adds one of five great debuffs, from Poison to Bleed, and no matter which player it lands on, they'll always be very happy with the result. There are also so many different synergies that can be created with the mutation, such as basic AoE attacks and debuff buffs, so if players are into visuals then they should definitely keep a mutated cat around.

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