The 7 Worst Devil Fruit Side Effects

One bite of the devil fruit is enough for the characters One piece gain extraordinary powers in exchange for their ability to swim. While some are lucky enough to consume devil fruits that grant powerful abilities, like Luffy's Hito Hito no Mi, others, like Kelly Funk's Jake Jake no Mi, are unlucky enough to receive strangely situational and strange devil fruit abilities.

One Piece Legendary Devil Fruits Final Saga

8 Legendary Devil Fruits in the Final Saga of One Piece, Rated

One Piece has some legendary Devil Fruits that could come into play in the Final Saga of One Piece.

However, regardless of ability, every Devil Fruit user v One piece he is prone to his common weaknesses. In addition, some Devil Fruits also come with unwanted side effects that can limit and negatively affect their users. Here's a look at the worst side effects of devil fruit in One Piece.

Nomi Nomi no Mi expands Dr. Vegapunk's brain endlessly

one piece worst devil fruit side effects-dr.vegapunk
one piece of the worst devil fruit side effects

Dr. Vegapunk is forever remembered for his contributions to science and history. He's probably the wisest man he's ever appeared in One piece for his incredible ability to easily consume and digest ancient and modern information. His inventions are also revolutionary, making him a vital asset to the Marine Corps and world government, especially when it comes to weapons development.

All this would not be possible without the devil fruit Dr. Vegapunka, Nomi Nomi No Mi, which grants him the ability to learn and remember information using his amazing brain. However, the more Dr. Vegapunk learns and stores information in his brain, the more he expands.

In fact, Dr. Vegapunk's brain expansion has no known limit as long as he is alive. The added weight eventually causes problems, so it wasn't long before Vegapunk decided to cut off most of his brain.

Hoya Hoya no Mi only works through Charlotte Daifuku's constant friction

one piece worst devil fruit side effects-charlotte daifuku
one piece of the worst devil fruit side effects

If it exists One piece version of Disney's Aladdin, that would be Charlotte Daifuku, user of the Hoya Hoya no Mi Devil Fruit. This devil fruit grants Charlotte Daifuku the ability to summon a powerful sentient genie from his unpredictable belt clip to aid him on the battlefield. Not only can this genie grow in size, but it can also turn into smoke as shown in the anime.

Unfortunately, in order for Charlotte Daifuku's genie to stay active, she has to constantly rub her body. Once it stops rubbing against its body, the genie ceases to exist and remains vulnerable. Without the fighting genie named Charlotte Daifuku, he just becomes a normal human despite using the devil fruit.

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Pam Pamu no Mi Gladius's hair is falling out

one piece of the worst devil fruit side effects-gladius
one piece of the worst devil fruit side effects

Even Devil Fruit users are not exempt from hair loss, especially Gladius from the Donquixote Pirates. While Gladius' devil fruit, Pamu Pamu No Mi, gives him an explosive ability, his Fashion Punch technique causes instant hair loss when used. Fashion Punc is best described as Gladius' technique to swell up his entire body and later cause a massive explosion that sends his deadly hair needles flying in different directions.

Shortly after Gladius uses the Fashion Punch, all of his hair falls out, resulting in a bushy hairstyle. Fortunately, Gladius doesn't seem to care too much about his hair, so the effect of this technique isn't a problem.

Beta Beta no Mi Trebol's nose is constantly running

one piece of the worst devil fruit side effects-trebol
one piece of the worst devil fruit side effects

It's unpleasant to have a cold, but not for Trebol from the Donquixote Pirates. Trebol's rhyme is more of a convenience for him, given his Devil Fruit ability, Beta Beta No Mi. This strange devil fruit gives Trebol the power to produce mucus and use it in battle. He mostly uses his slime power to limit enemy movements, but that doesn't mean he can't manipulate it for offensive purposes.

While Trebol's Devil Fruit ability sounds weak, its slime properties make it surprisingly annoying in battle. Imagine being hit by Trebol's sticky slime, which could even immobilize a ship. Combined with his constant cold, Trebol's phlegm ability becomes tremendously problematic.

Hobi Hobi no Mi traps sugar in the child's body

one piece of the worst devil fruit side effects-sugar
one piece of the worst devil fruit side effects

Playing with toys becomes a deadly hobby, all thanks to Sugar's devil fruit, Hobi Hobi No Mi. Hobi Hobi No Mi grants Sugar a strange but powerful ability to turn anyone into toys while erasing their existence from everyone's minds. It doesn't matter how tall or short Sugar's targets are, they shrink as soon as they turn into toys. Even Devil Fruit users lose their abilities, making them vulnerable.

However, Hobi Hobi No Mi also prevents the natural aging of sugar. After consuming a Devil Fruit, the sugar is effectively trapped in her current body and unable to grow or evolve any further. Sugar is currently 22 years old, but her body is still that of a 10-year-old.

Doku Doku no Mi gives Magellan intestinal problems

one piece worst devil fruit side effects-magellan
one piece of the worst devil fruit side effects

Former High Guardian Magellan hails from Impel Down and is one of the strongest characters Luffy has ever faced. One piece. He nearly killed Luffy with his Devil Fruit, Doku Doku No Mi, and even dispatched Blackbeard's crew with ease. Doku Doku no Mi transforms Magellan into a Poison Man, capable of using all kinds of poisons to attack his opponents.

Even though Magellan is immune to his Devil Fruit ability, it still causes him some intestinal problems that he can handle on his own. Because Magellan likes to eat food flavored with his poison, he doesn't die, but gets diarrhea instead. As a result, he often hangs out on the toilet and spends about 10 hours a day dealing with its effects.

Baku Baku No Mi makes Wapol permanently hungry

one piece of the worst devil fruit side effects-wapol
one piece of the worst devil fruit side effects

Wapol is one of the memorable characters in the early story arcs of One Piece. After all, he constantly antagonized Luffy and the straw pirates with his Devil Fruit Baku Baku No Mi for most of the Drum Island Arc. Baku Baku No Mi gives Wapolo the ability to eat anything, including living things, and then bring them into his body.

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If a Wapol chews on an object made of steel, it can assimilate it and later create steel weapons from its own body. However, Baku Baku No Mi also gives Wapol a feeling of eternal starvation, as nothing he eats can satisfy his hunger.


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Release date

October 20, 1999

Network

Fuji TV

directors

Hiroaki Miyamoto, Konosuke Uda, Junji Shimizu, Satoshi Itō, Munehisa Sakai, Katsumi Tokoro, Yutaka Nakajima, Yoshihiro Ueda, Kenichi Takeshita, Yoko Ikeda, Ryota Nakamura, Hiroyuki Kakudou, Takahiro Imayomura, Yashiôhiro Mayuū Shishido, Hidehiko Kadota, Sumio Watanabe, Harume Kosaka, Yasuhiro Tanabe, Yukihiko Nakao, Keisuke Onishi, Junichi Fujise, Hiroyuki Satou

Writers

Jin Tanaka, Akiko Inoue, Junki Takegami, Shinzo Fujita, Shouji Yonemura, Yoshiyuki Suga, Atsuhiro Tomioka, Hirohiko Uesaka, Michiru Shimada, Isao Murayama, Takuya Masumoto, Yoichi Takahashi, Momoka Toyoda

  • Cast placeholder image

    Mayumi Tanaka

    Monkey D. Luffy (voice)

  • Cast placeholder image

    Kazuya Nakai

    Roronoa Zoro (voice)


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